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Bavarostat

CAT: 0931-T69879-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69879-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2134109-20-7
Target
HDAC, Microtubule Associated, Others
Related Pathways
Others, Chromatin/Epigenetic, DNA Damage/DNA Repair, Cytoskeletal Signaling
Bioactivity
Bavarostata is a highly brain penetrant HDAC6 inhibitor (IC50=60nM) . Bavarostat exhibits excellent HDAC6 selectivity (>80-fold over all other Zn-containing HDAC paralogues), modulates tubulin acetylation selectively over histone acetylation, and has excellent brain penetrance.
Smiles
C(N(CC1=C(F)C=C(C(NO)=O)C=C1)C)C23CC4CC(C2)CC(C3)C4
Molecular Formula
C20H27FN2O2
Molecular Weight
346.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19210130-01Bavarostat
TRC-B112580-25MG3-Hydroxy-N-methoxy Bavarostat

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