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GSK2239633

CAT: 0931-T69830-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69830-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2181665-31-4
Target
Others
Related Pathways
Others
Bioactivity
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2 T-helper lymphocytes to the inflamed airways. Therefore, CCR4 provides an excellent target for anti-inflammatory therapy.
Smiles
N(S(=O)(=O)C=1SC(Cl)=CC1)C=2C=3C(N(CC4=CC(NC(CO)=O)=CC=C4)N2)=CC=CC3OC
Molecular Formula
C21H19ClN4O5S2
Molecular Weight
506.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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