SK-575

• Target:

  PROTACs|||PARP

• Related Pathways:

  PROTAC|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity:

  0.9939

• Bioactivity:

  SK-575 is a degradation agent targeting protein-hydrolyzed PARP1 chimera with anticancer and antitumor activity.SK-575 effectively inhibits the growth of cancer cells harboring BRCA1/2 mutations and selectively induces PARP1 degradation in cancer cells.

• Smiles:

  O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(C(=O)CCCCCCCCCCC(=O)NCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4

• Molecular Formula:

  C47H53FN8O8

• Molecular Weight:

  876.97

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2523016-96-6