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SK-575

CAT: 0931-T69596-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T69596-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2523016-96-6
Target
PROTACs, PARP
Related Pathways
PROTAC, DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9939
Bioactivity
SK-575 is a degradation agent targeting protein-hydrolyzed PARP1 chimera with anticancer and antitumor activity.SK-575 effectively inhibits the growth of cancer cells harboring BRCA1/2 mutations and selectively induces PARP1 degradation in cancer cells.
Smiles
O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(C(=O)CCCCCCCCCCC(=O)NCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4
Molecular Formula
C47H53FN8O8
Molecular Weight
876.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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463004SK-575
7583/5SK 575
A23938-5SK-575 5mg
HY-147101SK-575-NEG
466263SK 575-NEG
A23938-100SK-575 100mg
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A23938-10SK-575 10mg
BLG-P019-0058-[φ-575]-cAMP
GTR19275564-01CRBN ligand-575

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