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APBC

CAT: 0931-T69447-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69447-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
324054-99-1
Target
Others
Related Pathways
Others
Bioactivity
APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity.
Smiles
N(C(=O)C1=CC=C(C=C1)C2=CC=CC=C2)C3=C(C(N)=O)C=CC=C3
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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