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HMS607P03

CAT: 0931-T69365-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69365-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
361198-09-6
Target
Others, Sirtuin
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Others
Bioactivity
HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP90α.
Smiles
O=C1N(C2=NC=3C(S2)=CC=CC3)N=C(CSC4=CC=C(Cl)C=C4)C1=CNCC=5C=C6C(=CC5)OCO6
Molecular Formula
C26H19ClN4O3S2
Molecular Weight
535.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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