UC-857993

• Target:

  Others|||Ras|||ERK

• Related Pathways:

  MAPK|||Others|||GPCR/G Protein

• Bioactivity:

  UC-857993, a selective SOS1-Ras inhibitor (Kd=14.7 ?M, His6-SOS1cat), effectively suppresses catalytic activity. In addition to inhibiting ERK and Ras activation, it also hampers the growth of mouse embryonic fibroblasts (MEFs) .

• Smiles:

  C(O)(=O)C=1C=C2C=3N(C(C4C2C=CC4)C5=C(Cl)C=CC=C5)CC6C(C3C1)C=CC6

• Molecular Formula:

  C25H22ClNO2

• Molecular Weight:

  403.9

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  487001-04-7