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Pinafide

CAT: 0931-T69117-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69117-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
54824-20-3
Target
Others
Related Pathways
Others
Bioactivity
Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental tumors and shown to be inhibitor of two DNA viruses. Pinafide blocks cell growth by inhibiting DNA and RNA synthesis. It has been shown to bind to double-helical DNA by intercalation. Pinafide inhibited the activity of M. tuberculosis NAD+-dependent DNA ligase A at concentrations of 50 uM. At the chemical screening was found that pinafide inhibited B-Myb transcriptional activity in luciferase assays. The cross placental-barrier studies showed that 3H-pinafide was present in the 14-day fetuses.
Smiles
O=C1C=2C=3C(C(=O)N1CCN4CCCC4)=CC=CC3C=C(N(=O)=O)C2
Molecular Formula
C18H17N3O4
Molecular Weight
339.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5811669Pinafide

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