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E7974

CAT: 0931-T69003-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69003-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
610787-07-0
Target
Others
Related Pathways
Others
Bioactivity
E7974 is an analog of the sponge-derived anti-microtubule tripeptide hemiasterlin with antimitotic and potential antineoplastic activities. Hemiasterlin analog E7974 binds to the Vinca domain on tubulin, resulting in inhibition of tubulin polymerization and microtubule assembly; depolymerization of exsiting microtubules; inhibition of mitosis; and inhibition of cellular proliferation. This agent may have more affinity for the beta-3 tubulin isotype. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) .
Smiles
C(N[C@H](C(N([C@H](/C=C(/C(O)=O)\C)[C@@H](C)C)C)=O)C(C)(C)C)(=O)[C@@H]1N(C(C)C)CCCC1
Molecular Formula
C24H43N3O4
Molecular Weight
437.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19210933-01E7974

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