Iso-Fludelone

CAT: 0931-MF-0143624-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0143624-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
691868-19-6
Target
Others|||Microtubule Associated
Related Pathways
Cytoskeletal Signaling|||Others
Bioactivity
Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to other generations of epothilones, iso-fludelone exhibits increased stability, water solubility, potency, duration of action, tumor penetration as well as reduced toxicity. In addition, this agent is a not a substrate of the P-glycoprotein (P-gp), a multidrug resistance pump often overexpressed in cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) .
Smiles
C(=C\C=1C=C(C)ON1)(\C)/[C@@H]2C/C=C(\C(F)(F)F)/C/C=C/[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O2
Molecular Formula
C27H36F3NO6
Molecular Weight
527.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
MF-0008293-01(Iso) -Rilmakalim
MF-0008290-01(Iso) -ML399
MF-0153036Iso-oxypeucedanin
MF-0145385-01Ipconazole [ISO]
MF-0035501-01(iso) -BRD20322
MF-0008294-01(Iso) -Samixogrel
MF-0008284-01(Iso) -Dehydroemetine
MF-0008291-01(Iso) -MS4322
MF-0095489-01Iso-OMPA
MF-0144313-01Iso-Dehydrozingerone

Alternative Products

CatalogName
MBS5811415Iso-Fludelone
TRC-I816250-10MGIso-FK-506 (iso-Tacrolimus)
126715-01Iso Phorone-di-iso-cyanate
3122860Iso amyl acetate (Amyl acetate iso)
3120710Amyl acetate iso (Iso amyl acetate)
109350 100Iso Nicotinic Acid Hydrazide (Iso Niazid)
MBS3607514-01ISO-1
015028Iso Ganciclovir
015046(+/-) -Iso Myosmine
452488-01ISO 1

Popular Products