SIB-1893

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  SIB-1893 is a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 ?M at hmGlu5, compared with > 100 ?M at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. It positive allosteric modulator at mGlu4 receptors.

• Smiles :

  C(=C/C1=CC=CC=C1)\C=2N=C(C)C=CC2

• Molecular Formula :

  C14H13N

• Molecular Weight :

  195.26

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  7370-21-0