(±) -γ-Tocopherol

• Target:

  Others|||Endogenous Metabolite

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  (±) -?-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the synthesis of prostaglandin E2 (PGE2) induced by LPS in RAW 264.7 macrophages and by IL-1? in A549 cells. (±) -?-Tocopherol inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1?. Serum levels of (±) -?-tocopherol are decreased in patients with cardiovascular disease.

• Smiles:

  CC1=C2C(CCC(CCCC(CCCC(CCCC(C)C)C)C)(C)O2)=CC(O)=C1C

• Molecular Formula:

  C28H48O2

• Molecular Weight:

  416.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  7616-22-0