BI-4834

CAT: 0931-T68463-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T68463-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
876371-13-0
Target
Others
Related Pathways
Others
Bioactivity
BI-4834 is a potent and selective Polo-like kinase 1 (PLK1) inhibitor. BI-4834 is also analogue (or Me-Too) of BI-2536. In vitro test shows that BI 4834 inhibits PLK1 with IC50=7.6 nm, but with higher selectivity over the related enzyme PLK3 (IC50 198.4 nm) as BI-2536.
Smiles
C(C)(C)N1C=2C(N(C)C(=O)[C@H]1CC)=CN=C(NC3=C(OC)C=C(C(N[C@@H]4CC[C@H](CC4)N5C[C@@H](C)O[C@@H](C)C5)=O)C=C3)N2
Molecular Formula
C32H47N7O4
Molecular Weight
593.76
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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