A-849519

• CAS Number :

  904680-01-9

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.

• Smiles :

  C(O)(=O)C1=C2C(=CC=C1NS(=O)(=O)C3=C(/C=C\CN(C)C)C=C(F)C=C3)CCCC2

• Molecular Formula :

  C22H25FN2O4S

• Molecular Weight :

  432.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C