Nivocasan

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  Nivocasan, also known as GS-9450 and LB-84451, a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. GS-9450 treatment induced significant reductions in ALT levels in NASH patients.

• Smiles:

  C(N[C@@H]1[C@](CF)(O)OC(=O)C1)(=O)[C@]2(C(C)C)CC(=NO2)C=3C4=C(C=CN3)C=CC=C4

• Molecular Formula:

  C21H22FN3O5

• Molecular Weight:

  415.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  908253-63-4