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Annamycin

CAT: 0931-T68326-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T68326-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
92689-49-1
Target
Others, Antibiotic
Related Pathways
Others, Microbiology/Virology
Bioactivity
Annamycin is a semi-synthetic doxorubicin analogue annamycin with antineoplastic activity. Annamycin intercalates into DNA and inhibits topoisomerase II, resulting in the inhibition of DNA replication and repair and RNA and protein synthesis. This agent circumvents multidrug-resistance (MDR) transporters, including P-glycoprotein (P-gp) .
Smiles
OC=1C2=C([C@@H](O[C@H]3[C@H](I)[C@H](O)[C@@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C4C1C(=O)C=5C(C4=O)=CC=CC5
Molecular Formula
C26H25IO11
Molecular Weight
640.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C