Cep-5214

• Target :

  Others|||VEGFR

• Related Pathways :

  Others|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  CEP-5214 is a potent, low-nanomolar pan inhibitor of human VEGF-R tyrosine kinases, displaying IC50 values of 16,8, and 4 nM for VEGF-R1/FLT-1, VEGF-R2/KDR, and VEGF-R3/FLT-4, respectively, with cellular activity equivalent to the isolated enzyme activity.

• Smiles :

  O=C1NCC=2C1=C3C4=CC=CC=C4CC3=C5C2C6=CC(=CC=C6N5CCCO)COC(C)C

• Molecular Formula :

  C28H28N2O3

• Molecular Weight :

  440.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  402857-39-0