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Safironil

CAT: 0931-T67961-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T67961-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
134377-69-8
Target
MMP, Others
Related Pathways
Proteases/Proteasome, Others
Purity
0.9983
Bioactivity
Safironil is a novel antifibrotic compound and a competitive inhibitor of collagen synthesis. safironil inhibited in vitro experiments on fibroblast activation monitored by collagen I mRNA or smooth muscle alpha-actin levels, and fibrogenesis as judged by type I and type III collagen and laminin production. safironil had no effect on the size of liver granulomas without altering total hydroxyproline, but altered the pattern of fibrosis by increasing type III and decreasing type I collagen deposition.
Smiles
C(NCCCOC)(=O)C=1C=C(C(NCCCOC)=O)N=CC1
Molecular Formula
C15H23N3O4
Molecular Weight
309.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5810535Safironil

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