GRP78-IN-3

• Target:

  HSP

• Related Pathways:

  Metabolism|||Cytoskeletal Signaling

• Purity:

  0.9949

• Bioactivity:

  GRP78-IN-3, a potent small-molecule-competitive inhibitor of Hsp70 substrate binding and is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 ?M. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 ?M) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 ?M) .

• Smiles:

  C(N[C@H](C(NC1=NC=CS1)=O)[C@H](C)C)(=O)C2=CC=3C(N2)=CC=CC3

• Molecular Formula:

  C17H18N4O2S

• Molecular Weight:

  342.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2707510-30-1