GRP78-IN-3

CAT: 0931-T67897-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T67897-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2707510-30-1

Target

HSP

Related Pathways

Metabolism, Cytoskeletal Signaling

Purity

0.9949

Bioactivity

GRP78-IN-3, a potent small-molecule-competitive inhibitor of Hsp70 substrate binding and is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 μM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 μM) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 μM) .

Smiles

C(N[C@H](C(NC1=NC=CS1)=O)[C@H](C)C)(=O)C2=CC=3C(N2)=CC=CC3

Molecular Formula

C17H18N4O2S

Molecular Weight

342.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BA4195-10	GRP78-IN-3
E8ER1706-50	GRP78
70R-31218	GRP78 antibody
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