Cardioxane

CAT: 0931-T6467-05Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T6467-05Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

149003-01-0

Target

Others, Topoisomerase

Related Pathways

DNA Damage/DNA Repair, Others

Purity

0.998

Bioactivity

Cardioxane (ADR-529) is a cardio-protective drug.

Smiles

Cl.CC(CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1

Molecular Formula

C11H16N4O4·HCl

Molecular Weight

304.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Cardioxane

Dexrazoxane Hydrochloride is the hydrochloride salt of a bisdioxopiperazine with iron-chelating, chemoprotective, cardioprotective, and antineoplastic activities. After hydrolysis to an active form that is similar to ethylenediaminetetraacetic acid (EDTA), dexrazoxane chelates iron, limiting the formation of free radical-generating anthracycline-iron complexes, which may minimize anthracycline-iron complex-mediated oxidative damage to cardiac and soft tissues. This agent also inhibits the catalytic activity of topoisomerase II, which may result in tumor cell growth inhibition.

CAS Number	149003-01-0
PubChem CID	6918223
IUPAC Name	4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
Molecular Formula	C11H17ClN4O4
Molecular Weight	304.73
Topological Polar Surface Area	98.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Heavy Atom Count	20
Formal Charge	0
Complexity	404

SMILES

C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl

InChI

InChI=1S/C11H16N4O4.ClH/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14;/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19);1H/t7-;/m0./s1

InChIKey

BIFMNMPSIYHKDN-FJXQXJEOSA-N

Chemical Structure

2D Structure

CAS: 149003-01-0

CID: 6918223

Formula: C11H17ClN4O4

MW: 304.73

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	304.73
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	304.0938327
Monoisotopic Mass	304.0938327
Topological Polar Surface Area	98.8 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	404
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	2
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BUP13455-01	Cardioxane

Cardioxane

Chemical Information

Alternative Products

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