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FA16

CAT: 0931-T64357-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T64357-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ferroptosis
Related Pathways
Apoptosis
Purity
0.9981
Bioactivity
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2- (trifluoromethyl) benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system Xc-) -mediated exchange of intracellular glutamate for extracellular cystine.FA16 significantly inhibited tumor growth in a HepG2 xenograft tumor model. HepG2 xenograft tumor model significantly inhibited tumor growth.
Smiles
FC(F)(F)C(N=C1C2C=CC=C1)N2CC(CC3)CCN3C4=CC=C(S(N(C)C)(=O)=O)C=C4
Molecular Formula
C22H27F3N4O2S
Molecular Weight
468.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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