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PF-07038124 HCl

CAT: 0931-T60921L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T60921L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2415317-57-4
Target
IL Receptor, PDE
Related Pathways
Immunology/Inflammation, Metabolism
Purity
0.9966
Bioactivity
PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.
Smiles
O(CCC)C=1C=C(C=CC1OC)C=2C=C(C=NC2)[C@H]3CB(O)OC3.Cl
Molecular Formula
C18H23BClNO4
Molecular Weight
363.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

PF-07038124 HCl
CAS Number2415317-57-4
PubChem CID156900459
IUPAC Name3-[(4R)-2-hydroxyoxaborolan-4-yl]-5-(4-methoxy-3-propoxyphenyl)pyridine;hydrochloride
Molecular FormulaC18H23BClNO4
Molecular Weight363.6
Topological Polar Surface Area60.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count25
Formal Charge0
Complexity386
SMILES
B1(C[C@@H](CO1)C2=CN=CC(=C2)C3=CC(=C(C=C3)OC)OCCC)O.Cl
InChI
InChI=1S/C18H22BNO4.ClH/c1-3-6-23-18-8-13(4-5-17(18)22-2)14-7-15(11-20-10-14)16-9-19(21)24-12-16;/h4-5,7-8,10-11,16,21H,3,6,9,12H2,1-2H3;1H/t16-;/m0./s1
InChIKey
QHNSQBUGQNRYBR-NTISSMGPSA-N
Chemical Structure
2D Structure
2D structure of PF-07038124 HCl
CAS: 2415317-57-4
CID: 156900459
Formula: C18H23BClNO4
MW: 363.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight363.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass363.1408661
Monoisotopic Mass363.1408661
Topological Polar Surface Area60.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity386
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-144683PF-07038124
HY-144683A-01PF-07038124 (hydrochloride)
GTR19232021-01PF-07038124 HCl
MBS579460PF-03084014 (PF-3084014)
BA7029-25PF-04745637
A4374-5.1PF-3845
A8499-50PF-04691502
B8018-100PF 1022A
BA4631-10PF-739
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