Mithramycin A

• CAS Number :

  18378-89-7

• Target :

  DNA/RNA Synthesis|||GST|||Antibacterial|||Antibiotic

• Related Pathways :

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Oxidation-Reduction|||Microbiology/Virology

• Purity :

  0.9992

• Bioactivity :

  Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.

• Smiles :

  [H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)O[C@@H]1C[C@]([H])(Oc2cc3cc4C[C@@]([H])([C@H](OC)C(=O)[C@@H](O)[C@@H](C)O)[C@H](O[C@@]5([H])C[C@@H](O[C@@]6([H])C[C@@H](O[C@@]7([H])C[C@](C)(O)[C@H](O)[C@@H](C)O7)[C@@H](O)[C@@H](C)O6)[C@H](O)[C@@H](C)O5)C(=O)c4c(O)c3c(O)c2C)O[C@H](C)[C@H]1O

• Molecular Formula :

  C52H76O24

• Molecular Weight :

  1085.15

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C