2-Thio-UTP

• Target :

  Others|||P2Y Receptor

• Related Pathways :

  Others|||Neuroscience|||GPCR/G Protein

• Bioactivity :

  2-Thio-UTP is a selective P2Y2 receptor (purinergic receptor) agonist (EC50 = 50 nM) capable of inhibiting calcification potential, ?-smooth muscle actin expression, and pro-fibrotic gene expression in valvular interstitial cells (VICs) . It may be employed in studies of calcific aortic valve stenosis (CAVS) .

• Smiles :

  O[C@H]1[C@@H](O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O)N2C(=S)NC(=O)C=C2

• Molecular Formula :

  C9H15N2O14P3S

• Molecular Weight :

  500.21

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  35763-29-2