2-Thio-UTP

• Target:

  Others|||P2Y Receptor

• Related Pathways:

  Others|||Neuroscience|||GPCR/G Protein

• Bioactivity:

  2-Thio-UTP is a selective P2Y2 receptor (purinergic receptor) agonist (EC50 = 50 nM) capable of inhibiting calcification potential, ?-smooth muscle actin expression, and pro-fibrotic gene expression in valvular interstitial cells (VICs) . It may be employed in studies of calcific aortic valve stenosis (CAVS) .

• Smiles:

  O[C@H]1[C@@H] (O[C@H] (COP (OP (OP (=O) (O) O) (=O) O) (=O) O) [C@H]1O) N2C (=S) NC (=O) C=C2

• Molecular Formula:

  C9H15N2O14P3S

• Molecular Weight:

  500.21

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  35763-29-2