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Aclacinomycin A

CAT: 0931-T21502Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T21502Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
57576-44-0
Target
DNA/RNA Synthesis, Proteasome, Topoisomerase, Antibiotic
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Ubiquitination, Proteases/Proteasome, Microbiology/Virology
Purity
0.9943
Bioactivity
Aclacinomycin A (Aclarubicin) is a novel anthracycline antibiotic isolated from Streptomyces galilei with antitumor activity.Aclacinomycin A is an inhibitor of topoisomerases I and II and inhibits RNA activity.Aclacinomycin A has been used in the study of relapsed leukemia and advanced malignant lymphomas.
Smiles
C(OC)(=O)[C@@H]1C2=C([C@@H](O[C@H]3C[C@H](N(C)C)[C@H](O[C@H]4C[C@H](O)[C@H](O[C@@H]5O[C@@H](C)C(=O)CC5)[C@H](C)O4)[C@H](C)O3)C[C@@]1(CC)O)C(O)=C6C(=C2)C(=O)C=7C(C6=O)=C(O)C=CC7
Molecular Formula
C42H53NO15
Molecular Weight
811.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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