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Ap5dT

CAT: 0931-T212385-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212385-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
103137-88-8
Target
Nucleoside Antimetabolite/Analog
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
Ap5dT is an inhibitor of cytosolic thymidine kinase and mitochondrial enzyme, with Ki values of 0.12 μM and 0.50 μM, respectively. This compound is utilized in research related to acute myeloid leukemia.
Smiles
O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OP(OP(OP(OC[C@H]4O[C@H](C[C@@H]4O)N5C(=O)NC(=O)C(C)=C5)(=O)O)(=O)O)(=O)O)(=O)O)(=O)O)[C@H]1O
Molecular Formula
C20H30N7O23P5
Molecular Weight
891.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C