BI-9466

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  BI-9466 (Compound 2) is an antagonist of the NSD3-PWWP1 domain with a dissociation constant (Kd) of 144 µM. Designed as a negative control compound for BI-9321, BI-9466 lacks inhibitory activity against the NSD3-PWWP1 domain due to a more basic azacyclic structure introduced at the 5-position of BI-9321.

• Smiles:

  N=1C=C(C2=C(N=CN2C)C=3C(=CC(=CC3C)CN)C)N(C1)C

• Molecular Formula:

  C17H21N5

• Molecular Weight:

  295.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2538293-52-4