BAL-1516

• Target:

  NOD-like Receptor (NLR)

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  BAL-1516 is a brain-penetrant and highly selective NLRP3 inhibitor (IC50=14.2 nM) . It significantly inhibits the release of interleukin-1? and interleukin-18 in microglial neuroinflammation models (IC50=11-59 nM) . BAL-1516 holds potential for research in neurodegenerative diseases, such as Alzheimer's and Parkinson's, as well as systemic inflammatory disorders.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C