Products for Research Use Only

BAL-1516

CAT: 0931-T212112-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212112-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
BAL-1516 is a brain-penetrant and highly selective NLRP3 inhibitor (IC50=14.2 nM) . It significantly inhibits the release of interleukin-1β and interleukin-18 in microglial neuroinflammation models (IC50=11-59 nM) . BAL-1516 holds potential for research in neurodegenerative diseases, such as Alzheimer's and Parkinson's, as well as systemic inflammatory disorders.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C