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Linvemastat

CAT: 0931-T211998-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211998-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2389060-50-6
Target
MMP
Related Pathways
Proteases/Proteasome
Bioactivity
Linvemastat (Compound FC-4) is an orally active MMP-12 inhibitor with an IC50 of less than 10 nM and demonstrates high selectivity over MMP-1, -2, -3, -7, -9, -10, and -14. It significantly reduces lung fibrosis in a mouse model of bleomycin-induced unilateral pulmonary fibrosis and effectively alleviates kidney damage, interstitial inflammation, or fibrosis in a unilateral ureteral obstruction renal fibrosis model. Linvemastat is suitable for research into inflammatory diseases such as idiopathic pulmonary fibrosis (IPF), inflammatory bowel disease (IBD), and asthma.
Smiles
O=C1NC(=O)C(N1)C=2OC=CC2SC3=CC=C(OCC=4C=CN=C(C4)C)C=C3
Molecular Formula
C20H17N3O4S
Molecular Weight
395.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-171804Linvemastat

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