LC-MF-4

CAT: 0931-T211928-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211928-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
PROTACs|||ATPase|||FGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Membrane transporter/Ion channel|||PROTAC
Bioactivity
LC-MF-4 is a selective FGFR3 PROTAC degrader with a DC50 of 30.89 nM in KMS-11 cells. It inhibits the metabolic functions of FGFR3-TACC3 fusion-positive cancers by reducing ATP synthesis and suppressing mitochondrial biogenesis genes. LC-MF-4 demonstrates potent anti-tumor activity in the Ba/F3-FGFR3-TACC3 xenograft mouse model and is applicable for research on FGFR3 gene mutation cancers such as bladder cancer and urothelial carcinoma (UC) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T16068-01MF-438
T12024-01MF-094
T9622-01MF-766
T69744-01MF-095
T70465-01Mf 268
T71510-01MF-592
T12026-01MF 5137
T33372-01MF 13
T203158-01MF 961
T41026-01Biotin-LC-LC-NHS

Alternative Products

CatalogName
HY-174981LC-MF-4
314143-01Dynein LC 4
TRC-B395730-10MGLC-LC(+)-Biotin
535734-01Dynein LC 4 discontinued
C15515-01Dynein LC 4 Antibody
MBS3843717-01MF-094
456182-01MF 498
456183-01MF 63
6718/5(+/-)-MF 094
MBS5786467MF-766

Popular Products