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DPDL1-4

CAT: 0931-T211758-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211758-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
LYTACs, HSP, PD-1/PD-L1
Related Pathways
Apoptosis, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Metabolism, PROTAC, Immunology/Inflammation
Bioactivity
DPDL1-4 is a potent and selective eHSPTAC eHSP90PD-L1 degrader, with DC50 values of 7.77 μM (HeLa) and 6.52 μM (B16F10) . It links eHSP90 to target proteins, inducing lysosomal degradation. dPDL1-4 effectively degrades PD-L1 and inhibits tumor growth, making it useful for research in cervical cancer and melanoma.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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