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Pyrraline

CAT: 0931-T211753-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211753-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
74509-14-1
Target
Nrf2, Endogenous Metabolite, NF-κB
Related Pathways
Metabolism, NF-κB, Immunology/Inflammation
Bioactivity
Pyrraline is an activator of the Nrf2 pathway with antioxidant and anti-inflammatory properties. It enhances antioxidant enzymes like NAD (P) H oxidase (NQO1) and heme oxygenase-1 (HO-1) by activating the antioxidant response element (ARE), while inhibiting inflammation mediated by NFκB. Pyrraline holds potential for research in metabolic disorders, such as diabetic nephropathy, and cancer.
Smiles
C(CCC[C@@H](C(O)=O)N)N1C(CO)=CC=C1C=O
Molecular Formula
C12H18N2O4
Molecular Weight
254.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C