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Fentomycin

CAT: 0931-T211709-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211709-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ferroptosis
Related Pathways
Apoptosis
Bioactivity
Fentomycin is a dual-functional lipolysis-targeting chimera (LIPTAC) . It specifically targets plasma membrane phospholipids and, following endocytosis, activates lysosomal iron, which promotes phospholipid oxidation and degradation leading to ferroptosis. This compound effectively kills primary sarcoma and pancreatic ductal adenocarcinoma cells, particularly those subpopulations that are metastatic, drug-resistant, and exhibit high CD44 expression. Fentomycin shows antitumor activity.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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