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DNH28

CAT: 0931-T211558-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211558-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Caspase, NF-κB, Bcl-2 Family, p38 MAPK, Apoptosis
Related Pathways
Proteases/Proteasome, Apoptosis, NF-κB, MAPK
Bioactivity
DNH28 is a potent NF-κB and MAPK inhibitor with an IC50 value of 0.93 μM in HepG2 cells. It induces apoptosis by downregulating Bcl-2 and upregulating BAX and Cleaved-caspase-3 expression. DNH28 can arrest the cell cycle and inhibit cell migration, and is applicable for research in hepatocellular carcinoma (HCC) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-175037DNH28

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