Fluacrypyrim

CAT: 0931-T211395-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T211395-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

229977-93-9

Target

Apoptosis, Phosphatase, Parasite, STAT, MDM-2/p53

Related Pathways

Microbiology/Virology, Metabolism, Stem Cells, Apoptosis, JAK/STAT signaling

Bioactivity

Fluacrypyrim is an ester-based acaricide and functions as a STAT3 inhibitor. It significantly enhances the activity of protein tyrosine phosphatases (PTPs) and suppresses leukemia cell growth by inducing substantial G1 phase arrest and significantly reducing the levels of cyclin D1 protein and mRNA. Fluacrypyrim selectively inhibits the STAT3 signaling pathway, leading to growth arrest and apoptosis in STAT3-dependent cancer cells. It mainly alleviates radiation-induced hematopoietic system damage by preventing apoptosis in hematopoietic stem cells (HSCs) . Additionally, fluacrypyrim exhibits notable analgesic and anti-inflammatory effects by inhibiting uterine smooth muscle contraction and inflammatory responses.

Smiles

C(\C(OC)=O)(=C/OC)/C1=C(COC=2C=C(C(F)(F)F)N=C(OC(C)C)N2)C=CC=C1

Molecular Formula

C20H21F3N2O5

Molecular Weight

426.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-W414644	Fluacrypyrim

Fluacrypyrim

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