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Soficitinib

CAT: 0931-T211394-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211394-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2574524-67-5
Target
JAK
Related Pathways
Chromatin/Epigenetic, Stem Cells, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
Soficitinib (Compound 20) is a selective inhibitor targeting tyrosine kinase 2 (TYK2) and Janus kinase 2 (JAK2), with IC50 values of 0.5 nM and 1.2 nM, respectively. It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis, as well as inflammatory conditions.
Smiles
C[C@]12[C@](CN(C1)C3=NC(NC=4C=NN(C)C4)=NC=C3Cl)(CN(C(CC#N)=O)C2)[H]
Molecular Formula
C18H21ClN8O
Molecular Weight
400.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-177131Soficitinib

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