RegisterLogin

SR 142948 TFA

CAT: 0931-T211341-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211341-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Neurotensin Receptor
Related Pathways
GPCR/G Protein
Bioactivity
SR 142948 TFA is an orally active, selective non-peptide neurotensin receptor (NT) antagonist, displaying IC50 values of 1.19 nM in h-NTR1-CHO cells, 0.32 nM in HT-29 cells, and 3.96 nM in adult rat brain. In HT-29 cells, it counteracts NT-induced inositol monophosphate formation with an IC50 of 3.9 nM. It blocks NT-induced hypothermia, analgesia, and turning behavior in vivo and can cross the blood-brain barrier, making it useful for research in psychiatric disorders.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T23386SR 142948
T73677-01SR 142948 dihydrochloride
T204738-01SR 142948-C3-NHMe
T70861-01SR 27417A
T81108-01SR-1114
T88783-01SR 4330
T23393-01SR 49059
T28844-01SR 271425
T34704SR 42128
T4389-01SR-4370

Alternative Products

CatalogName
2309/1SR 142948
HY-107664BSR 142948 (TFA)
MBS5815769SR 142948 dihydrochloride
HY-107664A-01SR 142948 (dihydrochloride)
HY-170531SR 142948-C3-NHMe

Popular Products