KLHDC2-IN-1

• Target :

  Ligand for E3 Ligase

• Related Pathways :

  PROTAC

• Bioactivity :

  KLHDC2-IN-1 (Compound 6) is a ligand that specifically targets the ubiquitin E3 ligase KLHDC2 with a dissociation constant (Kd) of 160 nM. It can be synthesized into a PROTAC capable of effectively degrading BRD4 within cells.

• Smiles :

  O=C(O)C1=CC(Cl)=CC2=C1NC(C=3C=CC=C(OC(F)(F)F)C3)C4C2C5CCC4C5

• Molecular Formula :

  C22H19ClF3NO3

• Molecular Weight :

  437.84

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1005275-19-3