Products for Research Use Only

Y2641

CAT: 0931-T211220-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211220-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TNF, RANKL/RANK
Related Pathways
Apoptosis, NF-κB
Bioactivity
Y2641, a tetrahydro β-carboline derivative, is an orally active dual inhibitor of RANKL and TNF-α, with Kd values of 3.984 μM and 18.59 μM respectively. It suppresses RANKL-induced osteoclastogenesis and exhibits anti-inflammatory and cartilage-protective properties. Y2641 is applicable in osteoarthritis research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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