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Z218484536

CAT: 0931-T211164-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211164-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1223877-07-3
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
Z218484536 is a selective phosphoserine phosphatase (PSPH) inhibitor that can penetrate the blood-brain barrier. It binds to PSPH with an affinity (Kd) of approximately 0.23 μM. By doing so, Z218484536 reduces levels of L-serine and D-serine in astrocytes. It also inhibits spontaneous seizures without causing significant side effects and demonstrates effective antiepileptic properties in the temporal lobe epilepsy (TLE) model.
Smiles
O=C(N)NN=CC1=CNN=C1C=2C=CC(F)=CC2
Molecular Formula
C11H10FN5O
Molecular Weight
247.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
C21551-5mgZ218484536

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