MerTK-IN-3

• Target :

  TAM Receptor

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  MerTK-IN-3 (compound 11) is an orally active, selective inhibitor of MerTK, exhibiting IC50 values of 21.5 nM for MerTK and 991.3 nM for Tyro3. It is applicable in colon cancer research.

• Smiles :

  O=C(NC1=CC=C(OC=2N=CN=C3OC(C=4C=NN(C4)C)=C(C5=CC=CC(=C5)CN(C)C)C23)C=C1)C6=CN(N(C6=O)C7=CC=C(F)C=C7)C

• Molecular Formula :

  C36H31FN8O4

• Molecular Weight :

  658.68

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3029898-85-6