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TFCA

CAT: 0931-T211053-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211053-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
895700-18-2
Target
Liver X Receptor
Related Pathways
Metabolism
Bioactivity
TFCA is a liver X receptor α (LXRα) antagonist. It inhibits the coactivation of ligand-activated LXRα and suppresses the transcriptional expression of downstream target genes involved in fatty acid synthesis. By selectively inhibiting LXRα in the liver, TFCA reduces ligand-induced lipogenesis and fatty liver.
Smiles
O=C(C=CC1=CC=C(OC)C(OC)=C1)NC2=CC=C(C=C2)C(F)(F)F
Molecular Formula
C18H16F3NO3
Molecular Weight
351.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
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