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C105SR

CAT: 0931-T210448-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210448-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Caspase, Apoptosis
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
C105SR is a cyclophilin D (CypD) inhibitor targeting peptidyl-prolyl cis-trans isomerase (PPIase) . It has an IC50 value of 5 nM for inhibiting mitochondrial permeability transition pore (mPTP) opening. C105SR reduces apoptosis in hepatocytes induced by hypoxia-reoxygenation and boosts calcium retention capacity (CRC) . It demonstrates hepatoprotective effects in a mouse model of ischemia-reperfusion injury (IRI) .
Molecular Formula
C32H33BrN4O3S
Molecular Weight
633.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-157088C105SR

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