Products for Research Use Only

ETB

CAT: 0931-T210270-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210270-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
634589-47-2
Target
HSP
Related Pathways
Metabolism, Cytoskeletal Signaling
Bioactivity
ETB is a potent inhibitor of Hsp60 chaperone activity. It can impede the chaperone function of both wild-type proteins and the C237A and C447A mutant proteins. ETB binds to Hsp60 at Cys442, and the C442A mutant demonstrates resistance to ETB inhibition.
Smiles
C(/C(=C/CC/C=C/C(=C/C(/C(OC(C)(C)C)=O)=C\C)/C)/C)(=O)[C@@]12[C@@](O1)(C(C)(O)NC2=O)[H]
Molecular Formula
C24H33NO6
Molecular Weight
431.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C