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EpskA21

CAT: 0931-T210237-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210237-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Akt, PI3K
Related Pathways
Apoptosis, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Bioactivity
EpskA21 is an inhibitor of the PI3K/AKT signaling pathway and is capable of suppressing the proliferation of cancer cells including MCF-7, A549, MIA-PaCa-2, Panc-1, and HepG2, with an IC50 range of 1.3-7.24 μM. It can inhibit cell migration, arrest the cell cycle at the G2/M phase in MCF-7 cells and the S phase in MIA-PaCa-2 cells, and induce apoptosis in both MCF-7 and MIA-PaCa-2 cells. EpskA21 also leads to mitochondrial dysfunction.
Molecular Formula
C28H27NO6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-161858EpskA21

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