PSMA-trillium

CAT: 0931-T209977-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T209977-01Size:10 mg
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CAS Number
3036415-37-6
Target
PSMA
Related Pathways
Immunology/Inflammation
Bioactivity
PSMA-trillium is a PSMA-targeting compound comprising a PSMA-targeting molecule (PSMA binding agent), a Macropa chelator, and a pharmacokinetics-modulating group (PK modulator) . It acts as the non-radioactive variant of Actinium-225-PSMA-Trillium (BAY 3563254), boasting enhanced PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind with Ac through either the Macropa chelator or the radioactive isotope Actinium-225. Actinium-225-PSMA-Trillium effectively inhibits metastatic castration-resistant prostate cancer (mCRPC) .
Smiles
C(COCCOCCOCCC(N[C@@H](CCCCNC(NC1=CC=C(CCOC=2C=C(CN3CCOCCOCCN(CC=4N=C(C(O)=O)C=CC4)CCOCCOCC3)N=C(C(O)=O)C2)C=C1)=S)C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCCCNC(CCCC5=CC=C(I)C=C5)=O)C(O)=O)=O)=O)=O)N6C=C(N=N6)C7=CC(NC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=CC=C7
Molecular Formula
C106H156IN17O34S
Molecular Weight
2371.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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