TYM-3-98

• CAS Number :

  2820244-59-3

• Target :

  PI3K|||Apoptosis

• Related Pathways :

  Apoptosis|||PI3K/Akt/mTOR signaling

• Bioactivity :

  TYM-3-98 is a selective inhibitor of PI3K? with an IC50 of 7.1 nM. It inhibits the proliferation of B lymphoma cells by inducing apoptosis and suppressing the PI3K/AKT/mTOR signaling pathway. In mouse/rat models, TYM-3-98 displays favorable pharmacokinetic properties and antitumor activity without significant toxicity.

• Smiles :

  O=S(=O)(C=1C=CC=C(C1)N2N=C(C=3C=CC(Cl)=CC32)C(N4N=C(C=5C=CC(OC)=C(F)C5)C=6C(=NC=NC64)N)C)C

• Molecular Formula :

  C28H23ClFN7O3S

• Molecular Weight :

  592.05

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C