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NSCLC-IN-1

CAT: 0931-T209735-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209735-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Mitophagy, Ferroptosis
Related Pathways
Apoptosis, Autophagy
Bioactivity
NSCLC-IN-1 (Compound A10-2) targets transmembrane BAX inhibitor motif containing 6 (TMBIM6) to induce mitophagy and ferroptosis. It causes mitochondrial Ca2+ imbalance, resulting in mitochondrial damage. Additionally, NSCLC-IN-1 reduces intracellular glutathione (GSH) levels while increasing the accumulation of lipid peroxides (LPO) and malondialdehyde (MDA) . NSCLC-IN-1 is a potent anti-NSCLC compound.
Molecular Formula
C46H56N2O13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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