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SARS-CoV-2-IN-81

CAT: 0931-T209067-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209067-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
SARS-CoV, AAK1 (AP2 associated kinase 1)
Related Pathways
Microbiology/Virology, Neuroscience
Bioactivity
SARS-CoV-2-IN-81 (compound 12e) is an effective AAK1 inhibitor with an IC50 value of 9.38 nM. It demonstrates antiviral activity against SARS-CoV-2 by reducing AAK1-induced phosphorylation of threonine 156 on AP2M1 and disrupting the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection.
Molecular Formula
C25H20N4O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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