Products for Research Use Only

RS47

CAT: 0931-T207787-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T207787-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
301655-16-3
Target
Others, NF-κB
Related Pathways
Others, NF-κB
Purity
0.9876
Bioactivity
RS47 (Compound 1a) is a small molecule (Kd = 1.1 μM) that specifically targets RelB, selectively inhibiting the non-canonical NF-κB pathway by disrupting RelB binding to target DNA. It exhibits antitumour activity in vivo and in vitro and may be used in studies of colorectal cancer and B-cell lymphoma.
Smiles
OC1=CC=C(O)C(=C1)C(=NNC=2N=CN=C3SC4=C(C32)CCCC4)C
Molecular Formula
C18H18N4O2S
Molecular Weight
354.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C