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3-O-methyl Estradiol

CAT: 0931-T207770-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207770-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1035-77-4
Target
Others
Related Pathways
Others
Bioactivity
3-O-methyl Estradiol is a synthetic estrogen known for its ability to interfere with microtubule networks in V79 Chinese hamster cells, with an EC50 value of 9 μM. At a concentration of 20 μM, it inhibits the proliferation of these cells by 92%. Additionally, when male rats on a high-cholesterol diet are administered 3-O-methyl Estradiol (25 mg in a 0.2 ml solution, p.o.), it results in decreased serum cholesterol levels and increases body weight loss, suggesting feminizing effects. It has also been utilized as a standard for quantifying 17β-estradiol in hen urine.
Smiles
C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]
Molecular Formula
C19H26O2
Molecular Weight
286.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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